Scientists have transformed ordinary light into a healing tool by creating a unique gel that aids in bone regeneration.

Researchers from Pohang University of Science and Technology (POSTECH) in South Korea have developed a groundbreaking injectable hydrogel that utilizes visible light to repair bone defects. This innovation addresses significant issues associated with traditional bone regeneration methods, such as insufficient bonding strength and inability to maintain shape within the body, reports HospiMedica.

The hydrogel created by the scientists operates without the need for bone transplants, a common element in traditional treatment methods, providing dual functionality—adhesion and mineralization in a single application. The hydrogel's mechanism is activated by visible light, which is safe for human tissues. The light triggers the crosslinking process within the hydrogel while simultaneously promoting the formation of amorphous calcium phosphate—a mineral essential for bone growth.

The material consists of alginate from brown algae, an RGD peptide containing an adhesive protein from mussels, calcium ions, phosphonodiols, and a photoinitiator. This innovative composition ensures the hydrogel's structure is preserved post-injection and allows for effective bonding with surrounding tissues. Preclinical trials on animal models with femoral bone defects demonstrated the hydrogel's efficacy. After being introduced at the defect sites, the material successfully adhered, delivered the necessary minerals for bone tissue restoration, and facilitated healing.

The research findings were published in the journal Biomaterials and represent a significant advancement in the field of regenerative medicine. Professor Hyung Joon Cha, the lead researcher, emphasized the potential of this technology to revolutionize bone tissue regeneration. He stated that the hydrogel simplifies the treatment process by eliminating the need for separate adhesives and bone transplants, thereby streamlining and enhancing the overall effectiveness of bone restoration procedures.

The added value of this innovation is further enhanced by a broader trend in medical research towards integrating natural materials into treatment methods. Alginate, one of the hydrogel's components, is already widely used in therapeutic dressings and drug delivery systems due to its biocompatibility. Its application in bone regeneration may pave the way for other uses, such as soft tissue repair and cartilage regeneration, according to the authors.

Important! This article is based on the latest scientific and medical research and does not contradict them. The text is for informational purposes only and does not contain medical advice. For a diagnosis, please consult a physician.